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Closed (no longer recruiting)Last updated: 24 July 2023

BEACON: This phase II trial is evaluating the combination of three immunotherapy drugs (Atezolizumab, Bevacizumab and Cobimetinib) in patients diagnosed with High Grade Serous Ovarian Cancer, Fallopian Tube Cancer and Primary Peritoneal CancerA Phase II Study of Bevacizumab, Atezolizumab and Cobimetinib in Targeting the C1 Subtype of High Grade Serous Ovarian Cancer

Clinical summary

Summary

Participants will receive intravenous Bevacizumab (5mg/kg) every two weeks, intravenous Atezolizumab (840mg) every two weeks from Cycle two onwards and Cobimetinib (60mg per day) every day for 21 days.

Conditions

This trial is treating patients with High Grade Serous Ovarian Cancer, Fallopian Tube Cancer Primary Peritoneal Carcinoma.

Cancer

Female Reproductive System Cancers Female Reproductive System

Age

People18+

Phase

II

Trial Acronym

BEACON

More information

Trial Identifiers

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Commercial Sponsor

Peter MacCallum Cancer Centre

Scientific Title

A Phase II Study of Bevacizumab, Atezolizumab and Cobimetinib in Targeting the C1 Subtype of High Grade Serous Ovarian Cancer

Eligibility

Exclusion

  • You have certain types of non-cancer medical conditions.
  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.
  • You have previously been treated (or are currently being treated) on a clinical trial.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

Participating hospitals

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Closed hospitals

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Cancer Council Victoria would like to acknowledge the traditional custodians of the land on which we live and work. We would also like to pay respect to the elders past and present and extend that respect to all other Aboriginal people.