InformationClinical trials have complex eligibility criteria.
Always talk to your clinician about you’re interest in participating in a trial.
Learn why

Optimise reading forHealth ProfessionalsPatients

RecruitingLast updated:15 March 2022

Interfant 06: This trial is studying how well different therapies work in treating infants with newly diagnosed acute leukemiaInternational collaborative treatment protocol for infants under one year with acute lymphoblastic or biphenotypic leukaemia (Other IDs: CDR0000570260, DCOG-INTERFANT-06, EudraCT 2005-004599-19, CCLG-LK-2006-10).

Clinical summary

Summary

Infant acute lymphoblastic leukaemia (ALL) is a rare disease and comprises about 4% of childhood ALL. Whereas the outcome of older children with ALL has improved to 80-85% event-free survival (EFS) infants with ALL have a worse prognosis.In 1999, a large international collaborative study group was started to develop common treatment protocols for infant ALL to try to improve the outcome for these very young children.The primary aim of the study is to assess the role of early intensification of two acute myeloid leukemia induction blocks versus standard IB protocol directly after induction, in a randomised way in MR and HR patients.The secondary aims of the study are:to assess the overall outcome of the Interfant-06 protocol compared to the historical control series, especially the Interfant-99, to assess the outcome of LR, MR and HR patients as compared to the historical control series in Interfant99, to study which factors have independent prognostic value and to assess the role of stem cell transplant (SCT) in HR patients.

Age

People0 - 1

Phase

Unknown

Trial Acronym

Interfant 06

More information

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Commercial Sponsor

Dutch Childhood Oncology Group

Scientific Title

International collaborative treatment protocol for infants under one year with acute lymphoblastic or biphenotypic leukaemia (Other IDs: CDR0000570260, DCOG-INTERFANT-06, EudraCT 2005-004599-19, CCLG-LK-2006-10).

Eligibility

Inclusion

  • You have certain types of non-cancer medical conditions.
  • You have had certain treatments, surgical procedures or drugs.

Exclusion

  • You have been diagnosed with cancer, but have not received any treatment.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

Participating hospitals

Recruiting hospitals

InformationTell us if you find this trial availability is not accurate.Report inaccuracy

Get Support

Example

Cancer Connect

Speak with someone who has cancer clinical trial experience.

Learn more

Example

Cancer Council’s cancer nurses

If you need cancer information and practical support for yourself, a carer, family or friend, contact Cancer Council’s experienced cancer nurses on 131120.

Learn more

Example

Information for family, friends and carers

When you are considering a cancer clinical trial, it is a good idea to discuss it with your family, friends or carers.

Learn more