This phase II trial is investigating different chemotherapy combinations for the treatment of elderly patients that have Acute Myeloid Leukaemia .
This trial is treating patients with acute myeloid leukaemia.
This is a systemic therapy trial.
You may be able to join this trial if:
- You have been diagnosed with cancer, but have not received any treatment.
You may be excluded from this trial if:
- You have a certain disease or psychological condition.
- You have been diagnosed with a prior or secondary type of cancer.
- You have had certain treatments, surgical procedures or drugs.
- You have previously been treated (or are currently being treated) on a clinical trial.
Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.
Clinical Summary Read More
Trial Identifiers
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Scientific Title
An ALLG Phase 2 study to Investigate Novel Triplets to Extend Remission with VENetoclax in Elderly (INTERVENE) Acute Myeloid Leukaemia
Cooperative Group
Australasian Leukaemia and Lymphoma Group (ALLG)
Summary
This trial includes a dose finding Run-in phase and a randomised phase. Eligible patients enrolled in the Run-in phase of the trial will received Low dose cytarabine (LDAC) and venetoclax, in combination with either midostaurin OR pracinostat to determine a recommended phase 2 dose. Eligible patients enrolled in the randomised phase of the trial will receive LDAC and venetoclax alone, or in combination with either midostaurin OR pracinostat at the recommended phase 2 dose.
Recruiting Hospitals Read More
Not Recruiting Hospitals Read More