This phase 2 trial is assessing the clinical benefit of adding a statin (Simvastatin) to standard chemotherapy and radiotherapy to treat patients with rectal cancer before surgery .
This trial is treating patients with Rectum Cancer.
This is a systemic therapy.
You may be able to join this trial if:
- You are able to swallow medication by mouth.
You may be excluded from this trial if:
- You have a certain disease or psychological condition.
- You have been diagnosed with a prior or secondary type of cancer.
- You have had certain treatments, surgical procedures or drugs.
Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.
Clinical Summary Read More
Use the hyperlinks, where available to access additional clinical trial information.
A randomized, placebo-controlled phase II trial of Simvastatin in addition to standard chemotherapy and radiation in preoperative treatment for rectal cancer
Australasian Gastro-Intestinal Trials Group (AGITG)
Other Non-Commercial Sponsor
Cancer Council NSW
Patients eligible to participate in this trial will receive daily oral doses of Simvastatin or a placebo, which will be taken for 90 days and commenced 1 week prior to the first radiation dose.
Recruiting Hospitals Read More