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RecruitingLast updated:15 August 2023

This phase I study is evaluating how safe, tolerable and effective a new targeted therapy (CC-95251) is alone, and in combination with another drug (azacitidine) in people with relapsed or refractory acute myeloid leukaemia, and people with myelodysplastic syndromesA Phase 1, Open-label, Dose Finding Study of CC-95251 Alone and in Combination With Antineoplastic Agents in Subjects With Acute Myeloid Leukemia and Myelodysplastic Syndromes

Clinical summary

Summary

Eligible participants will be allocated to one of two experimental arms. In Experimental Arm A, participants will receive CC-95251 as monotherapy. In Experimental Arm B, participants will receive CC-95251 in combination with azacitidine.

Age

People18+

Phase

I

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Trial Identifiers

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Commercial Sponsor

Bristol-Myers Squibb (BMS)

Scientific Title

A Phase 1, Open-label, Dose Finding Study of CC-95251 Alone and in Combination With Antineoplastic Agents in Subjects With Acute Myeloid Leukemia and Myelodysplastic Syndromes

Eligibility

Inclusion

  • You have certain types of non-cancer medical conditions.
  • You have had certain treatments, surgical procedures or drugs.

Exclusion

  • You have been diagnosed with cancer, but have not received any treatment.
  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.
  • You have had treatment, but your cancer has come back.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

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