Clinical trials are an important way to improve treatment for people with cancer. While most are continuing during the COVID-19 pandemic, the period of time that clinical trials are available and recruiting may change quickly. If you would like to get involved in a clinical trial, speak to your treatment team or the health service where the clinical trial is being undertaken, to confirm it is open and appropriate for you. For cancer information and support, call Cancer Council's experienced cancer nurses on 13 11 20 Monday to Friday from 9am-5pm.

CAMPFIRE : A Randomized, Open-Label Phase 1/2 Study Evaluating Ramucirumab in Pediatric Patients and Young Adults With Relapsed, Recurrent, or Refractory Desmoplastic Small Round Cell Tumor

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

One/TwoPhase One/Two

1-29Age 1-29

Sarcoma<br/>CancersCancer LocationSarcoma
Cancers

Systemic therapy | SarcomaSoft Tissue Sarcoma

Trial Overview Read MoreRead more

This phase I/II trial is evaluating how safe and effective targeted therapy (ramucirumab) is when combined with chemotherapy (cyclophosphamide and vinorelbine), compared to chemotherapy alone, in children and young adults with desmoplastic small round cell tumours (DSRCT).
 

This trial is treating patients with desmoplastic small round cell tumours.

This is a systemic therapy trial.

You may be able to join this trial if:

  • You are able to swallow medication by mouth.
  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.
  • You have had treatment, but your cancer has come back.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have had certain treatments, surgical procedures or drugs.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Randomized, Open-Label Phase 1/2 Study Evaluating Ramucirumab in Pediatric Patients and Young Adults With Relapsed, Recurrent, or Refractory Desmoplastic Small Round Cell Tumor

Commercial Sponsor

Eli Lilly and Company

Summary

This is a randomised, open-label trial with experimental and active comparator arms. Participants in the Experimental Arm will receive ramucirumab (administered intravenously [IV]) in combination with cyclophosphamide (administered orally) and vinorelbine (administered via IV). Participants in the Active Comparator Arm will receive cyclophosphamide (administered orally) and vinorelbine (administered via IV).

Recruiting Hospitals Read MoreRead more

Royal Childrens Hospital
Parkville
Trial Coordinator
CCC.ClinicalTrials@rch.org.au

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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