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Closed (no longer recruiting)Last updated: 15 August 2023

AMG144: This phase I trial is trying to understand whether a new intravenous drug is safe and tolerable for the treatment of patients with advanced cancerA Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 256 in Patients With Advanced Solid Tumors

Clinical summary

Summary

This is a dose escalation and expansion trial. Eligible patients will be assigned to receive AMG 256 as an intravenous infusion in order to determine a maximum tolerated dose or recommended phase 2 dose.

Conditions

This trial is treating patients with advanced solid cancers.

Cancer

Advanced Cancers Advanced

Age

People18 - 100

Phase

I

Trial Acronym

AMG144

More information

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Commercial Sponsor

AMGEN

Scientific Title

A Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 256 in Patients With Advanced Solid Tumors

Eligibility

Inclusion

  • Your cancer has spread to other parts of the body.

Exclusion

  • You have certain types of non-cancer medical conditions.
  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.
  • You have previously been treated (or are currently being treated) on a clinical trial.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

Participating hospitals

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Closed hospitals

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RAP

Cancer Council Victoria would like to acknowledge the traditional custodians of the land on which we live and work. We would also like to pay respect to the elders past and present and extend that respect to all other Aboriginal people.