Clinical trials have complex eligibility criteria.Always talk to your clinician about you’re interest in participating in a trial.Learn why
HP Version - Clinical trials have complex eligibility criteria.Always talk to your clinician about you’re interest in participating in a trial.Learn why
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RecruitingLast updated: 5 February 2024
Clinical summaryEligibilityParticipating hospitalsSupport
This is a non-randomised, parallel assignment study that has three parts. Part A involves the anticancer drug Brentuximab vedotin and chemotherapy drugs doxorubicin, vinblastine, and dacarbazine (this combination is also known as A+AVD) being administered separately via intravenous infusion (IV) to participants with advanced stage classical Hodgkin lymphoma (cHL) during each treatment cycle. Participants in Part A will also be treated with granulocyte colony stimulating factor (G-CSF) following every dose of A+AVD for 6 cycles of treatment. Part B involves the anticancer drug Brentuximab vedotin, immunotherapy drug nivolumab, and chemotherapy drugs doxorubicin and dacarbazine (this combination is also known as AN+AD) being administered separately via IV to participants with Stage II bulky mediastinal disease and Stage III or IV cHL during each treatment cycle. Part C involves AN+AD being administered separately via IV in participants with Stage I or II cHL with non-bulky mediastinal disease during each treatment cycle.
This trial is treating patients with Hodgkin's Lymphoma.
Haematological
12+
II
Use the hyperlinks, where available to access additional clinical trial information.
Seagen Inc.
Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
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Treatment-naïve, classic Hodgkin lymphoma (cHL) participants
Clinical trials have complex eligibility criteria.
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