Latest Trials

Systemic therapy trial

IMPACT : A Phase I, Open-Label, Multi-Center, Dose Escalation and Expansion Study to Evaluate...

This phase I trial will begin to understand how safe and tolerable a combination therapy (containing a new cancer drug, IMP4297, and a type of chemotherapy) is in people diagnosed with advanced solid cancer, including small cell lung cancer

Status : Recruiting

Systemic therapy trial

AtTEnd : Phase III Double-blind Randomized Placebo Controlled Trial of Atezolizumab in Combination...

This phase III trial will evaluate whether it is more or less effective to use an immunotherapy, in combination with chemotherapy, to treat women with advanced or recurrent endometrial cancer

Status : Recruiting

Systemic therapy trial

Lynk 003 : A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of Olaparib...

This phase III trial is trying to evaluate the safety and effectiveness of a targeted cancer drug, given alone and in combination with another targeted cancer drug or chemotherapy, for the treatment of patients with a colorectal cancer that has spread to other parts of the body

Status : Recruiting

Systemic therapy trial

Open-label, Randomized Phase II Trial With BNT111 and Cemiplimab in Combination or as...

This Phase II trial is evaluating how safe and effective a targeted therapy (BNT111) is when used by itself or combined with immunotherapy (cemiplimab) in people with anti-PD1-refractory or relapsed melanoma

Status : Recruiting

Systemic therapy trial

HELIOS-A: A Phase 3 Global, Randomized, Open-label Study to Evaluate the Efficacy and...

This Phase III is evaluating the effectiveness of a targeted therapy (vutrisiran) in people with hereditary transthyretin amyloidosis

Status : Recruiting

Systemic therapy trial

KEYNOTE-991 : A Phase 3, Randomized, Double-blind Trial of Pembrolizumab (MK-3475) Plus Enzalutamide...

This phase III trial is trying to understand the safety and effectiveness of using an immunotherapy (pembrolizumab) and hormone therapy (Enzalutamide plus androgen deprivation therapy) to treat patients with metastatic hormone sensitive prostate cancer (mHSPC)

Status : Recruiting

Systemic therapy trial

COALITION : A Multicentre Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher Risk...

This Phase I/II trial is trying to understand how safe and tolerable a targeted therapy drug (glofitamab) is in combination with chemotherapy in people with higher-risk Diffuse Large B-Cell Lymphoma or High Grade B-Cell Lymphoma

Status : Recruiting

Systemic therapy trial

NKARTA : A Phase 1 Study of NKX101, an Activating Chimeric Receptor Natural Killer Cell Therapy,...

This Phase I trial is evaluating how safe and tolerable an experimental targeted therapy (NKX101) is in people with acute myeloid leukaemia or myelodysplastic syndromes

Status : Recruiting

Systemic therapy trial

TAILOR : Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot...

This trial is evaluating individually tailored treatment plans in people with advanced cancers who are accessing targeted therapy cancer drugs through compassionate access

Status : Recruiting

Systemic therapy trial

A Phase I/II, Open-Label, Multicenter Study Evaluating the Safety, Tolerability,...

This trial is trying to understand how safe and well tolerated a new form of targeted therapy is, in people with B-Cell Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukaemia that has got worse or not responded to previous treatment

Status : Recruiting

 

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