Summary
Who is it for?
You may be eligible for this trial if you are aged over 50 who has been diagnosed with early-stage breast cancer and will be undergoing radiation therapy following surgery for your cancer.
Study details
All participants in this study will receive a type of breast cancer treatment called Accelerated Partial Breast Irradiation (APBI) using a method called Volumic Modulated Arc Therapy (VMAT).
Only the part of the breast where the cancer has been surgically removed will receive radiation therapy (partial bresast irradiation or PBI), rather than the whole breast (whole breast irradiation). This approach can reduce the toxic effects of radiation therapy.
The treatment starts within 12 weeks after breast-convserving surgery and involves a planning session with a CT scan to help plan the treatment, which takes about an hour. After this, participants will take part in five daily 15-minute treatment sessions over one week.
Participants in this study will be randomly allocated (by chance) to receive one of two doses of treatment (26Gy or 30 Gy).
All participants will then be followed up for 3 years to assess quality of life and if there are any recurrences of cancer.
It is hope that this study will help determine if participant quality of life is th same with a higher dose compared to a slightly lower dose. This will help then decide the best dose for future patients with early breast cancer.