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No longer recruiting (closed or complete)Last updated: 27 May 2025

SABR One Stop: This pilot study is assessing how feasible it is to deliver quality assured single-fraction (SF) stereotactic ablative radiotherapy (SABR) pathway for early-stage non-small cell lung cancerStereotactic Ablative Radiotherapy (SABR) One Stop Service for Lung Cancer: A pilot study for early-stage Non-small cell lung cancer (NSCLC).

Trial purpose

Medical clipboardCancer treatment

Tumor type

Lung Cancers Lung cancer

Age

People18+

Trial acronym

SABR One Stop

Clinical summary

Summary

You may be eligible for this study if you are over the age of 18, are referred for single-fraction stereotactic ablative radiotherapy (SF-SABR) and have early stage non-small cell lung cancer.

Participating in this research involves undergoing your SABR treatment according to a different timeframe to what would normally happen. It also involves completing a short, anonymised survey after your treatment to provide feedback on your experience of the treatment.

You visit the hospital for the simulation scan which the treatment team uses to plan and design your treatment. This happens whether or not you are participating in the study. However, if you are not on the study, you go home after this scan and the team works on the plan in the background. You are called back for treatment approximately two weeks later and undergo treatment as an outpatient.

If you choose to participate in the study, your treatment will happen within the same visit, customised to on eof two options based on your travel requirements:

  1. If most convenient to attend for a morning planning CT scan, treatment will be delivered in the afternoon. There will be a gap of roughly 4-6 hours between scan and treatment. You are free to leave the hospital during this time. Total time in the hospital may be anywhere from approximately 2-8 hours on that day.
  2. If most convenient to attend for an afternoon planning CT scan, treatment will be delivered the next morning.

You will also meet with one of our nurse specialists who will discuss arrangements for your follow up after the treatment, and give you printed information about this and the experience survey. You will be provided with a $50 voucher for the 'Super Eight' cafe on the ground floor at Peter Mac to cover the cost of beverages and/or meals on the day of your attendance. A follow-up consultation with your radiation oncologist will also be arranged approximately two weeks later. This can be arranged as a 'virtual' telehealth appointment if you prefer.

It is hoped this research will contribute to the development of streamlined, patient-centred treatment pathways and improve access to timely, high-quality SABR, potentially enhancing health outcomes for people with early-stage NSCLC.

Conditions

This trial is treating people with early-stage non-small cell lung cancer

Eligibility

Inclusion

Adult Patients (min 18 years old)
Referred for SABR for either: Histologically-confirmed lung cancer and/or MDM Recommendation for empiric SABR based on clinical and radiological features which are deemed to represent lung cancer
Staging is T1-T2 N0M0 based on CT and/or PET/CT imaging o Diagnostic imaging performed within 6 weeks of study enrolment
Non-central tumour location (i.e. Gross Tumour Volume (GTV) at least 2cm from proximal bronchial tree)
Provides informed consent
Fit to attend for the length of time required, whether fully independent, or by spending some or all of this time with nursing care in the radiotherapy trolley bay.

Exclusion

 

Inability to complete patient experience survey based on cognitive impairment or other comorbidities

Lack of suitable diagnostic images which is an important screening tool as part of the preplanning stage

Unable to meet Peter MacCallum Cancer Centre clinical goals for SF SABR based on virtual pre-planning

Previous radiotherapy which may overlap with the current lesion planned for treatment

Synchronous malignancy also planned for oncological treatment

Inclusion

  • Your cancer has not spread to other parts of the body (localised).

Exclusion

  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.
Message

Clinical trials have complex eligibility criteria, and other criteria may apply for this trial. Ask your doctor about whether this trial could be right for you.

Participating hospitals

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No longer recruiting (closed or complete) hospitals

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More information

Trial Identifiers

Information on this page is partially produced from ANZCTR *. View further details about this trial on the registry via the links below:

Trial sponsor

Peter MacCallum Cancer Centre

Scientific Title

Stereotactic Ablative Radiotherapy (SABR) One Stop Service for Lung Cancer: A pilot study for early-stage Non-small cell lung cancer (NSCLC).

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