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RecruitingLast updated: 1 October 2025

DINE-PC: Assessing the feasibility of a dietetics intervention and nutritional evaluation for adults with pancreatic cancer

Trial purpose

Medical clipboardSide effect and wellbeing

Tumor type

Upper gastrointestinal tract Cancers Upper gastrointestinal tract

Age

People18+

Trial acronym

DINE-PC

Clinical summary

Summary

Malnutrition, sarcopenia (loss of muscle mass and strength), and cachexia (weight loss and fatigue) are common concerns for people with pancreatic cancer, causing increased risk of comorbidities and may affect their ability to respond to cancer treatments. This study aims to assess the feasibility and effectiveness of an out-patient dietetics program on nutritional status and quality of life in individuals with pancreatic cancer.

You may be eligible for this study if you are aged 18 years or older, have been diagnosed with pancreatic cancer and are due to begin your cancer therapy within the next month.

You will be assessed by a dietitian within the first month of your treatment. Basic health and nutrition information will be collected including your age, weight, cancer stage and treatment, symptoms impacting your nutrition (such as nausea, vomiting, or treatment side effects), and diet history.

Individual nutrition recommendations will be provided to optimise your nutritional intake, which might involve consuming oral nutrition supplements. If you have not started therapy, education will be provided regarding your upcoming treatment and how this might impact your nutrition afterwards. The number of times you will be seen by a dietitian will depend on your nutrition status and how much support you require.

You will be requested to complete questionnaires to help researchers understand your nutritional status, quality of life, and satisfaction with the dietetics program.

It is hoped this research will determine that dietary counselling for patients with pancreatic cancer is feasible and acceptable to these patients. This pilot study will assess whether there is potential benefit in delivering this service to a greater number of patients with pancreatic cancer in a larger randomised trial. 

Conditions

This trial is treating people with pancreatic cancer who are planning to begin or have just begun treatment with systemic therapies (medicines or drugs)

Eligibility

Inclusion

 

Participants must meet all the following criteria:
- Aged at least 18 years at the time of consent
- Planned for systemic therapy
- Provide written informed consent prior to any study procedures and agree to adhere to all protocol requirements
- Confirmed histological or cytological diagnosis of pancreatic cancer.
- No later than one-month post commencement of systemic treatment, including chemotherapy, biological therapy, radiotherapy, or targeted therapy for pancreatic cancer.
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 2.
- Has a life expectancy of greater or equal to 6 months.

Exclusion

Participants must not meet any of the following criteria:
- Currently enrolled in a weight management program, receiving nutritional counselling, or part of another nutrition-related study/program.

Inclusion

  • You have been diagnosed with cancer, but have not received any treatment.
  • You have had a certain type of treatment or surgical procedure.
  • You have the type of cancer, symptoms, or health risks that this clinical trial is focused on.
Message

Clinical trials have complex eligibility criteria, and other criteria may apply for this trial. Ask your doctor about whether this trial could be right for you.

Participating hospitals

Recruiting hospitals

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More information

Trial Identifiers

Information on this page is partially produced from ANZCTR *. View further details about this trial on the registry via the links below:

Trial sponsor

Epworth HealthCare

Scientific Title

Assessing the feasibility of a dietetics intervention and nutritional evaluation for adults with pancreatic cancer

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