Trial purpose
Cancer treatment
Tumor type
Genitourinary
Age
18+
Clinical summary
Summary
Each subject will have a TURBT procedure performed per standard of care procedure, which will be followed by the study intervention - Continuous Bladder Irrigation (CBI) for up to two hours after procedure. Six samples of discarded bladder irrigation will be collected from each participant (N=20) immediately after TURBT and after the completion of each liter of normal saline 0.9% irrigation (1 to 5 L) for a total of 120 samples.
Conditions
This trial is treating people with bladder cancer
Eligibility
Inclusion
- Patients age 18 years and older diagnosed with a bladder mass on cystoscopy or imaging study
- Primary bladder tumor occurrence
Exclusion
- Patients with unresectable bladder tumors, as determined at the time of diagnosis or TURBT , or imaging concerning of T2 or higher disease
- Patients with bladder perforation at the time of TURBT, which is a contraindication to CBI
- Patients from vulnerable populations, including but not limited to impaired subjects, pregnant women, prisoners, family members of the study team
- Any previous history of bladder tumor resection or intravesical chemotherapy/immunotherapy
- History of previous pelvic radiation
- Bladder tumor volume > 5 cm, involvement of prostatic urethra, or any evidence of hydronephrosis on imaging
Exclusion
- You have had certain treatments, surgical procedures or drugs.
Clinical trials have complex eligibility criteria, and other criteria may apply for this trial. Ask your doctor about whether this trial could be right for you.
More information
Trial Identifiers
Information on this page is partially produced from ClinicalTrials.gov *. View further details about this trial on the registry via the links below:
Trial sponsor
Case Comprehensive Cancer Center
Scientific Title
Continuous Bladder Irrigation Following Transurethral Resection of Bladder Tumors
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