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RecruitingLast updated: 13 February 2023

AKESO – AK112-01: This phase 1 trial is evaluating the effectiveness and safety of a novel immunotherapy (AK112) for the treatment of patients with advanced solid tumoursA Phase 1a/1b, Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK112 in Subjects with Advanced Solid Tumors

Clinical summary

Summary

This trial will consist of a Dose Escalation phase, where the maximum tolerated dose of AK112 will be determined, and a Dose Expansion phase with patients that have specific tumour types. All patients eligible to participate in either part of this trial will receive intravenous administration of AK112 every 2 weeks.

Conditions

This trial is treating patients with Advanced solid tumours.

Cancer

Advanced Cancers Advanced

Age

People18+

Phase

I

Trial Acronym

AKESO – AK112-01

More information

Trial Identifiers

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Commercial Sponsor

Akesobio

Scientific Title

A Phase 1a/1b, Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK112 in Subjects with Advanced Solid Tumors

Eligibility

Exclusion

  • You have certain types of non-cancer medical conditions.
  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

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The Victorian Cancer Trials Link is supported by the Victorian Government through the Victorian Cancer Agency.

RAP

Cancer Council Victoria would like to acknowledge the traditional custodians of the land on which we live and work. We would also like to pay respect to the elders past and present and extend that respect to all other Aboriginal people.