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RecruitingLast updated: 13 February 2023

AKESO – AK112-01: This phase 1 trial is evaluating the effectiveness and safety of a novel immunotherapy (AK112) for the treatment of patients with advanced solid tumoursA Phase 1a/1b, Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK112 in Subjects with Advanced Solid Tumors

Clinical summary

Summary

This trial will consist of a Dose Escalation phase, where the maximum tolerated dose of AK112 will be determined, and a Dose Expansion phase with patients that have specific tumour types. All patients eligible to participate in either part of this trial will receive intravenous administration of AK112 every 2 weeks.

Conditions

This trial is treating patients with Advanced solid tumours.

Cancer

Advanced Cancers Advanced

Age

People18+

Phase

I

Trial Acronym

AKESO – AK112-01

More information

Trial Identifiers

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Commercial Sponsor

Akesobio

Scientific Title

A Phase 1a/1b, Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK112 in Subjects with Advanced Solid Tumors

Eligibility

Exclusion

  • You have certain types of non-cancer medical conditions.
  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.
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Clinical trials have complex eligibility criteria.

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