Clinical trials have complex eligibility criteria.Always talk to your clinician about you’re interest in participating in a trial.Learn why
HP Version - Clinical trials have complex eligibility criteria.Always talk to your clinician about you’re interest in participating in a trial.Learn why
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Closed (no longer recruiting)Last updated: 7 February 2024
Clinical summaryEligibilityParticipating hospitalsSupport
This is an open-label, multi-center, accelerated titration design study. Participants will receive TG-1801 as an intravenous infusion over 1-hour, in 4-week (28 day) cycles.
This trial is treating patients with B-Cell Lymphoma.
Haematological
18+
I
Use the hyperlinks, where available to access additional clinical trial information.
TG Therapeutics, Inc
A Phase 1 First-in-Human Study of Bispecific Antibody TG-1801 in Subjects With B-Cell Lymphoma
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Adequate organ function defined as:
Subjects receiving cancer therapy (i.e. chemotherapy, radiation therapy, immunotherapy, biologic therapy, hormonal therapy, surgery and/or tumor embolization) or any investigational drug within 21 days of Day 1 of Cycle 1 (42 days for prior mitomycin C or a nitrosourea).
a. Corticosteroid therapy started at least 7 days prior to Cycle 1 Day 1 (prednisone ≤ 10 mg daily or equivalent) is allowed as clinically warranted. Topical or inhaled corticosteroids are permitted.
Subjects who have not recovered (≤ Grade 1 or at baseline) from adverse events due to previous therapy, except for alopecia and Grade 2 neuropathy due to previous cancer therapy.
Note: Toxicity that has not recovered to ≤ Grade 1 is allowed if it meets the inclusion requirements for laboratory parameters defined above.
Any severe or uncontrolled illness or other conditions that could affect their participation in the study including, but not limited to:
Clinical trials have complex eligibility criteria.
Ask your doctor if this trial could be right for you.
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If you need cancer information and practical support for yourself, a carer, family or friend, contact Cancer Council’s experienced cancer nurses on 131120.
When you are considering a cancer clinical trial, it is a good idea to discuss it with your family, friends or carers.
Thank you for helping us to increase accuracy of the trial. Our team will validate the information and update the information as soon as possible.