NCT03628677 : A Phase 1 Study to Evaluate the Safety and Tolerability of AB154 Monotherapy and Combination Therapy in Participants With Advanced Malignancies

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

OnePhase One

18+Age Over 18

Advanced CancersCancer LocationMulti-Cancer
Trial

Systemic therapy | Bowel (colorectum),Breast,Female reproductive organs,Head and neck,Lung,Skin,Stomach and upper gastrointestinal tract,Urinary systemBladder,Breast,Colon,Colorectum,Endometrium,Gastro-oesophageal junction ,Head and neck,Lung,Melanoma (Ocular),Melanoma (Skin),Merkel cell,Non-Small Cell Lung Cancer,Oesophagus,Ovary,Rectum,Renal cell carcinoma,Stomach

Trial Overview Read MoreRead more

This phase I trial is evaluating the safety and recommended dose of an immunotherapy drug alone and in combination for the treatment of patients with advanced solid cancers.
 

This trial is treating patients with advanced solid cancers.

This is a systemic therapy trial.

You may be able to join this trial if:

  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have been diagnosed with a prior or secondary type of cancer.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Phase 1 Study to Evaluate the Safety and Tolerability of AB154 Monotherapy and Combination Therapy in Participants With Advanced Malignancies

Commercial Sponsor

Arcus Biosciences, Inc.

Summary

This is a non-randomised trial, in which patients will be sequentially assigned to receive Varying Doses of AB154 Monotherapy, and varying doses of AB154 in combination with the selected dose of AB122.

Not Recruiting Hospitals Read MoreRead more

Closed

Olivia Newton-John Cancer Wellness & Research Centre
Heidelberg
Ms Samantha Chakar
samantha.chakar@austin.org.au
03 9496 3088

Border Medical Oncology
Albury
Ms Nyree Sarakis
Nsarkis@bordermedonc.com.au
02 6064 1493

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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