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RecruitingLast updated: 11 November 2022

The RaDD study: This phase I trial is assessing simultaneous radiotherapy and immunotherapy (with durvalumab) in patients with relapsed Diffuse Large B Cell LymphomaPhase I Dose Escalation Study of Radiotherapy and Durvalumab in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Clinical summary

Summary

Patients enrolled in this trial will be allocated to a radiotherapy dose and site cohort at registration. There will be no intra-patient dose or site escalations. The number of anatomical sites and dose of radiotherapy will be escalated subject to safety. A fixed dose of durvalumab will be administered intravenously every 4 weeks.

Conditions

This trial is treating patients with Diffuse Large B-Cell Non-Hodgkin Lymphoma.

Cancer

Blood Cancers Blood

Age

People18+

Phase

I

Trial Acronym

The RaDD study

More information

Trial Identifiers

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Commercial Sponsor

Austin Health

Scientific Title

Phase I Dose Escalation Study of Radiotherapy and Durvalumab in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Eligibility

Inclusion

  • You have had a certain type of treatment or surgical procedure.
  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.

Exclusion

  • You have certain types of non-cancer medical conditions.
  • You have had certain treatments, surgical procedures or drugs.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

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