This phase III trial is comparing an immunotherapy to standard of care treatment in adults who have been diagnosed with B-cell Non-Hodgkin Lymphoma and have failed prior immunochemotherapy.
This trial is treating patients with B-Cell Non-Hodgkin Lymphoma.
This is a systemic therapy trial.
You may be able to join this trial if:
- You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.
You may be excluded from this trial if:
- You have a certain disease or psychological condition.
- You have had certain treatments, surgical procedures or drugs.
Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.
Clinical Summary Read More
Use the hyperlinks, where available to access additional clinical trial information.
Tisagenlecleucel Versus Standard of Care in Adult Patients With Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma: A Randomized, Open Label, Phase III Trial
Eligible patients will be randomised to receive the investigator's choice of optional platinum-based immunochemotherapy followed by (1) lymphodepleting chemotherapy (containing fludarabine with cyclophosphamide or bendamustine) and a single dose of Tisagenlecleucel OR (2, in responding patients only) high dose chemotherapy and autologous hematopoietic stem cell transplant (HSCT).
Not Recruiting Hospitals Read More