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A Randomized Phase 3 Comparison of IMO-2125 With Ipilimumab Versus Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma
Idera Pharmaceuticals, Inc.
In this trial, participants will be randomised into one of two arms of treatment. In Arm A, participants will receive four 3mg/kg doses of Ipilimumab intravenously over 90 minutes in Weeks 1, 4, 7 and 10. In Arm B, participants will receive the Arm A treatment plus an IMO intratumoral injection administered as 9 doses in Weeks 1, 2, 3, 5, 8, 11, 16, 20 and 24.