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Closed (no longer recruiting)Last updated: 31 May 2023

This phase I/II trial is evaluating the safety and effectiveness of an oral drug (BMS-813160) alone or in combination with immunotherapy (Nivolumab) and/or chemotherapy in patients with advanced solid cancers, particularly colorectal cancer or pancreatic cancerA Phase 1b/2 Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Patients With Advanced Solid Tumors

Clinical summary

Summary

This is a non-randomised trial, in which patients will be assigned to one of seven experimental arms, receiving BMS-813160 alone or as a combination therapy. Combination therapies will include one or more of the following: Nivolumab, Nab-paclitaxel, Gemcitabine, 5-fluoroucil (5-fu), leucovorin and/or Irinotecan.

Conditions

This trial is treating patients with colorectal or pancreatic cancer.

Cancer

Advanced Cancers Advanced

Age

People18+

Phase

I/II

More information

Trial Identifiers

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Commercial Sponsor

Bristol-Myers Squibb (BMS)

Scientific Title

A Phase 1b/2 Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Patients With Advanced Solid Tumors

Eligibility

Inclusion

  • You are able to swallow medication by mouth.
  • Your cancer has spread to other parts of the body.

Exclusion

  • You have certain types of non-cancer medical conditions.
  • You have had certain treatments, surgical procedures or drugs.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

Participating hospitals

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Closed hospitals

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