This phase III trial is evaluating how well active surveillance and four different chemotherapy drugs (bleomycin, carboplatin, etoposide, or cisplatin) work in treating paediatric or adult patients with germ cell tumours.
This trial is treating patients with germ cell tumours.
This is a systemic therapy trial.
You may be excluded from this trial if:
- You have a certain disease or psychological condition.
- You have had certain treatments, surgical procedures or drugs.
Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.
Clinical Summary Read More
Use the hyperlinks, where available to access additional clinical trial information.
A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors
Children's Oncology Group
Participants in this study will be randomised into one of five arms. Participants in Experimental Arms I-IV will receive different combinations of chemotherapy drugs as described in the Schedule. In the Experimental Low-Risk (observational) arm, patients with stage I, grade 2 or 3 ovarian teratoma or low-risk stage I malignant germ cell tumours will undergo observation until eligibility criteria are met, at which point they will be transferred to the standard risk arm.
Recruiting Hospitals Read More