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Closed (no longer recruiting)Last updated: 2 October 2023

TRITON3: This phase III trial is comparing an oral drug (Rucaparib) with standard treatment in patients who have metastatic castration-resistant prostate cancerA Multicenter, Randomized, Open Label Phase 3 Study of Rucaparib Versus Physician's Choice of Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Associated With Homologous Recombination Deficiency

Clinical summary

Summary

The purpose of this study is to determine how patients with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib verses treatment with physician's choice of abiraterone acetate, enzalutamide, or docetaxel.

Conditions

This trial is treating patients with Prostate Cancer.

Cancer

Urinary System Cancers Urinary System

Age

People18+

Phase

III

Trial Acronym

TRITON3

More information

Trial Identifiers

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Commercial Sponsor

Clovis Oncology, Inc.

Scientific Title

A Multicenter, Randomized, Open Label Phase 3 Study of Rucaparib Versus Physician's Choice of Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Associated With Homologous Recombination Deficiency

Eligibility

Inclusion

  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.

Exclusion

  • You have been diagnosed with a prior or secondary type of cancer.
  • You have certain types of non-cancer medical conditions.
  • You have had certain treatments, surgical procedures or drugs.
Message

Clinical trials have complex eligibility criteria.

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Closed hospitals

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