In this phase II trial, patients with severe aplastic anaemia who have been treated with, but not responded to immunosuppressive therapy (IST), will receive a new drug (avatrombopag) as a potential treatment for their condition.
This trial is treating patients with aplastic anaemia.
This is a systemic therapy trial.
You may be excluded from this trial if:
- You have a certain disease or psychological condition.
- You have been diagnosed with a prior or secondary type of cancer.
Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.
Clinical Summary Read More
Trial Identifiers
Use the hyperlinks, where available to access additional clinical trial information.
Scientific Title
Avatrombopag iN Relapsed or Refractory severe Aplastic Anaemia as EXtra Therapy – a Bayesian Optimal Phase II study
Other Non-Commercial Sponsor
Monash University
Summary
Eligible patients will receive oral avatrombopag at a maximum dose of 60mg per day, for up to 180 days. Dose will be adjusted every 2 weeks guided by reticulocyte count, platelet count/platelet transfusion and neutrophil count.
Recruiting Hospitals Read More