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RecruitingLast updated:12 September 2023

LARK: This study is evaluating how accurate and effective radiation therapy for either primary or secondary liver cancer is when utilising a new type of real-time tumour localisation (called Kilovoltage Intrafraction Monitoring)LARK: Liver Ablative Radiotherapy Utilising Kilovoltage Intrafraction Monitoring (KIM)

Clinical summary


Eligible participants will receive liver radiation therapy called Stereotactic Ablative Body Radiotherapy (SABR). Kilovoltage Intrafraction Monitoring (KIM) tracking will be tested during mock treatment. If it is found to be successful, it will be used throughout treatment. If it is found to be unsuccessful, cone beam CT imaging will be used instead.

Treatment Type

Radiotherapy,Systemic therapy (chemotherapy, hormone therapy or immunotherapy)


People18 - 85


Not applicable

Trial Acronym


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Trial Identifiers

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Commercial Sponsor

University of Sydney

Scientific Title

LARK: Liver Ablative Radiotherapy Utilising Kilovoltage Intrafraction Monitoring (KIM)



  • You have certain types of non-cancer medical conditions.
  • You have had certain treatments, surgical procedures or drugs.


  • You are currently receiving treatment for your cancer.
  • You have been diagnosed with cancer, but have not received any treatment.
  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.
  • Your cancer has not spread to other parts of the body.

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

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