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RecruitingLast updated:15 August 2023

NEON-1: This Phase I trial is evaluating a targeted therapy (ALPN-202) in people with advanced solid cancers, or refractory lymphoma.An Open-label Study of ALPN-202 in Subjects With Advanced Malignancies (NEON-1)

Clinical summary

Summary

This is an open-label dose escalation and expansion study in adults with advanced solid tumours or lymphoma, refractory or resistant to standard therapy, or without available standard or curative therapy. All participants will receive ALPN-202. Multiple dose levels and dose regimens will be administered.

Age

People18 - 75

Phase

I

Trial Acronym

NEON-1

More information

Trial Identifiers

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Commercial Sponsor

Alpine Immune Sciences, Inc.

Scientific Title

An Open-label Study of ALPN-202 in Subjects With Advanced Malignancies (NEON-1)

Eligibility

Inclusion

  • You have certain types of non-cancer medical conditions.
  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.

Exclusion

  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.
  • Your cancer has not spread to other parts of the body.
  • Your cancer has spread to other parts of the body.
Message

Clinical trials have complex eligibility criteria.

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Participating hospitals

Recruiting hospitals

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