REDIRECT : A Phase II Open-label Multicenter Study to Assess the Efficacy and Safety of AFM13 in Patients With Relapsed or Refractory CD30-positive Peripheral T-cell Lymphoma or Transformed Mycosis Fungoides (REDIRECT)

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

TwoPhase Two

18+Age Over 18

Blood<br/>CancersCancer LocationBlood
Cancers

Systemic therapy | Blood / Myeloma / LymphomaT-Cell Lymphoma

Trial Overview Read MoreRead more

This phase II trial is trying to understand the safety and effectiveness of a targeted therapy drug (AFM13) in people with CD30-positive T-cell lymphoma.
 

This trial is treating patients with CD30-positive T-cell lymphoma.

This is a systemic therapy trial.

You may be able to join this trial if:

  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.
  • You have had treatment, but your cancer has come back.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have had certain treatments, surgical procedures or drugs.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

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Scientific Title

A Phase II Open-label Multicenter Study to Assess the Efficacy and Safety of AFM13 in Patients With Relapsed or Refractory CD30-positive Peripheral T-cell Lymphoma or Transformed Mycosis Fungoides (REDIRECT)

Commercial Sponsor

Affimed GmbH

Summary

This is a non-randomised trial with three cohorts, all receiving AFM13 via weekly intravenous infusions of 200mg. Cohort A will be PTCL (peripheral T cell lymphoma) patients with CD30 expression ≥10%. Cohort B will be PTCL (peripheral T cell lymphoma) patients with CD30 expression ≥1% to <10%. cohort="" c="" will="" be="" tmf="" (transformed="" mycosis="" fungoides)="" patients="" with="" cd30="" expression="">

Recruiting Hospitals Read MoreRead more

Monash Health Haematology Research Unit
Clayton
Ms Anita Cummins
anita.cummins@monashhealth.org
03 9594 4044

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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