PARC : A Phase I/II Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) in Relapsed/Refractory Cancers of Children and Young Adults

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

One/TwoPhase One/Two

1-25Age 1-25

Advanced CancersCancer LocationMulti-Cancer
Trial

Systemic therapy | Blood / Myeloma / Lymphoma,Brain and spinal cord,SarcomaAcute Lymphoblastic Lymphoma,Acute Myeloid Leukaemia,Glioma,Leukaemia,Neuroblastoma,Sarcoma

Trial Overview Read MoreRead more

This phase I/II trial evaluates the safety and activity of an anti-cancer drug in children or young people with relapsed or refractory leukaemia, neuroblastoma, sarcoma or high grade glioma.
 

This trial is treating patients with leukaemia, neuroblastoma, sarcoma or high grade glioma (brain cancer).

This is a systemic therapy trial.

You may be able to join this trial if:

  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have had certain treatments, surgical procedures or drugs.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Phase I/II Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) in Relapsed/Refractory Cancers of Children and Young Adults

Other Non-Commercial Sponsor

University of Birmingham

Summary

Eligible patients will be assigned to experimental groups dependant on their condition; Leukaemia, Neuroblastoma, Sarcomas and High Grade Glioma. Each group will receive a weekly IV infusion of PEG- BCT-100.

Recruiting Hospitals Read MoreRead more

Royal Childrens Hospital
Parkville
Trial Coordinator
CCC.ClinicalTrials@rch.org.au

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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