Clinical trials have complex eligibility criteria.Always talk to your clinician about you’re interest in participating in a trial.Learn why
HP Version - Clinical trials have complex eligibility criteria.Always talk to your clinician about you’re interest in participating in a trial.Learn why
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Closed (no longer recruiting)Last updated: 7 February 2024
Clinical summaryEligibilityParticipating hospitalsSupport
Eligible participants will undergo up to 4 weeks of treatment with Darovasertib (300mg, twice a day as a starting dose) after fulfilling inclusion/exclusion criteria and consent. Select participants will undergo adjuvant treatment for 6 months based on their initial response.
This trial is treating patients with occular melanoma (uveal).
Head and Neck
18+
II
NADOM
Use the hyperlinks, where available to access additional clinical trial information.
Anthony Joshua, FRACP
Neoadjuvant/Adjuvant Trial of Darovasertib in Ocular Melanoma
Head and neck
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Patients with a prior history of or clinically stable concurrent malignancy are eligible for enrolment provided the malignancy is clinically insignificant, no treatment is required, and the patient is clinically stable
Patient has adequate organ function at screening:
Female patients of childbearing potential must be non-pregnant, non-lactating, and have a negative serum human chorionic gonadotropin pregnancy test result within 28 days prior to the first study drug administration.
Patients who are receiving treatment with medications that cannot be discontinued prior to study entry and that are considered to be any of the following (see Appendix 4):
Females who are pregnant or breastfeeding:
Impaired cardiac function or clinically significant cardiac diseases, including any of the following:
Clinical trials have complex eligibility criteria.
Ask your doctor if this trial could be right for you.
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Speak with someone who has cancer clinical trial experience.
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If you need cancer information and practical support for yourself, a carer, family or friend, contact Cancer Council’s experienced cancer nurses on 131120.
When you are considering a cancer clinical trial, it is a good idea to discuss it with your family, friends or carers.
Thank you for helping us to increase accuracy of the trial. Our team will validate the information and update the information as soon as possible.