ARCUS Breast/Gyne : A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Breast and Gynecologic Malignancies

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

OnePhase One

Advanced CancersCancer LocationMulti-Cancer
Trial

Systemic therapy | Breast,Female reproductive organsBreast,Ovary

Trial Overview Read MoreRead more

This phase I trial is testing different chemotherapy and immunotherapy combinations in patients with advanced triple-negative breast cancer or ovarian cancer.
 

This trial is treating patients with triple negative breast cancer or ovarian cancer.

This is a systemic therapy trial.

You may be able to join this trial if:

  • Your cancer has spread to other parts of the body.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.
  • You have previously been treated (or are currently being treated) on a clinical trial.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Breast and Gynecologic Malignancies

Commercial Sponsor

Arcus Biosciences, Inc.

Summary

This is a dose escalation and expansion trial. The Dose Escalation phase will inform the Dose Expansion dose level for AB928 alone and in combination with IPI-549. Patients enrolled in the Dose Expansion phase will be assigned to received the recommended dose level of AB928 and/or IPI-549 in combination with standard PLD or NIP chemotherapy. Patients will be assigned to an Arm based on their tumour diagnosis.

Recruiting Hospitals Read MoreRead more

Peninsula & South Eastern Haematology and Oncology Group
Frankston
Mr Albert Goikman
ag@paso.com.au
03 9771 8918

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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