NCT03549000 : A Phase I/Ib, Open-label, Multi-center, Study of NZV930 as a Single Agent and in Combination With PDR001 and/or NIR178 in Patients With Advanced Malignancies

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

OnePhase One

18+Age Over 18

Advanced CancersCancer LocationMulti-Cancer
Trial

Systemic therapy | Bowel (colorectum),Breast,Female reproductive organs,Lung,Stomach and upper gastrointestinal tract,Urinary systemBreast,Colon,Colorectum,Lung,Non-Small Cell Lung Cancer,Ovary,Pancreas,Rectum,Renal cell carcinoma

Trial Overview Read MoreRead more

This phase I trial is evaluating a new intravenous drug (NZV930) alone and in combination with two other drugs (one intravenous and one oral) for the treatment of specific advanced cancers.
 

This trial is treating multiple types of cancer including Non-Small Cell Lung Cancer, Triple Negative Breast Cancer, Pancreatic Ductal Adenocarcinoma, Colorectal Cancer Microsatellite Stable, Ovarian Cancer and Renal Cell Carcinoma.

This is a systemic therapy trial.

You may be able to join this trial if:

  • Your cancer has spread to other parts of the body.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have been diagnosed with a prior or secondary type of cancer.
  • You have had certain treatments, surgical procedures or drugs.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Phase I/Ib, Open-label, Multi-center, Study of NZV930 as a Single Agent and in Combination With PDR001 and/or NIR178 in Patients With Advanced Malignancies

Commercial Sponsor

Novartis Pharmaceuticals

Summary

The purpose of this study is to assess the safety, tolerability, and preliminary anti-tumor activity of experimental medication NZV930 alone and when combined with PDR001 and/or NIR178, in patients with advanced cancers. The main conditions or diseases eligible for inclusion in this trial include: Non-Small Cell Lung Cancer, Triple Negative Breast Cancer, Pancreatic Ductal Adenocarcinoma, Colorectal Cancer Microsatellite Stable, Ovarian Cancer and Renal Cell Carcinoma.

Recruiting Hospitals Read MoreRead more

PCCTU (Parkville Cancer Clinical Trials Unit) *
Parkville
Ms Marian Lieschke
marian.lieschke@petermac.org
03 8559 7140

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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