M13-833 : A Phase 1 Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

OnePhase One

<25Age Under 25

Advanced CancersCancer LocationMulti-Cancer
Trial

Systemic therapy | Blood / Myeloma / Lymphoma,Brain and spinal cordAcute Lymphoblastic Leukaemia,Acute Myeloid Leukaemia,B-Cell Non Hodgkin Lymphoma,Diffuse Large Cell Lymphoma,Follicular Lymphoma,Leukaemia,Lymphoma,Mantle Cell Lymphoma,Neuroblastoma,T-Cell Lymphoma

Trial Overview Read MoreRead more

This phase I trial is evaluating an oral drug (venetoclax) with or without chemotherapy in children and young adults with relapsed or refractory malignancies.
 

This trial is treating multiple types of cancer including Acute Lymphoblastic Leukaemia (ALL), Acute Myeloid Leukaemia (AML), Non-Hodgkin's Lymphoma or Neuroblastoma.

This is a systemic therapy trial.

You may be able to join this trial if:

  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have had certain treatments, surgical procedures or drugs.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Phase 1 Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

Commercial Sponsor

AbbVie

Summary

In this trial, Venetoclax will be administered orally once daily (QD) with various doses and dosing regimens, with or without chemotherapy at the discretion of the investigator.

Recruiting Hospitals Read MoreRead more

Royal Childrens Hospital
Parkville
Ms Kahlia Fox
kahlia.fox@mcri.edu.au
(03) 9345 6214

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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