AGCT1531 : A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

ThreePhase Three

<49Age Under 49

Advanced CancersCancer LocationMulti-Cancer
Trial

Systemic therapy | Female reproductive organs,Urinary systemGerm cell tumour,Ovary,Testis

Trial Overview Read MoreRead more

This phase III trial is evaluating how well active surveillance and four different chemotherapy drugs (bleomycin, carboplatin, etoposide, or cisplatin) work in treating paediatric or adult patients with germ cell tumours.
 

This trial is treating patients with germ cell tumours.

This is a systemic therapy trial.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have had certain treatments, surgical procedures or drugs.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors

Cooperative Group

Children's Oncology Group

Summary

Participants in this study will be randomised into one of five arms. Participants in Experimental Arms I-IV will receive different combinations of chemotherapy drugs as described in the Schedule. In the Experimental Low-Risk (observational) arm, patients with stage I, grade 2 or 3 ovarian teratoma or low-risk stage I malignant germ cell tumours will undergo observation until eligibility criteria are met, at which point they will be transferred to the standard risk arm.

Recruiting Hospitals Read MoreRead more

Monash Children's Cancer Centre
Clayton
Ms Irina Arzhintar
Irina.Arzhintar@monashhealth.org
(03) 8572 3490

Royal Childrens Hospital
Parkville
Ms Kahlia Fox
kahlia.fox@mcri.edu.au
(03) 9345 6214

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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