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CompletedLast updated: 21 December 2023

This phase I/II trial is testing the drug BMS-986012 in combination with Platinum and Etoposide therapy, as first line treatment for people with extensive Small Cell Lung Cancer (SCLC)A Phase 1/2 Randomized Trial of BMS-986012 in Combination With Platinum and Etoposide as First-line Therapy in Extensive-Stage Small Cell Lung Cancer

Clinical summary

Summary

The purpose of this this study is to administer BMS-986012 in Combination with Platinum and Etoposide as First-line Therapy in Extensive Small Cell Lung Cancer.

Conditions

This trial is treating patients with Small Cell Lung Cancer (SCLC).

Cancer

Lung Cancers Lung cancer

Age

People18+

Phase

I/II

More information

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Trial sponsor

Bristol-Myers Squibb (BMS)

Scientific Title

A Phase 1/2 Randomized Trial of BMS-986012 in Combination With Platinum and Etoposide as First-line Therapy in Extensive-Stage Small Cell Lung Cancer

Eligibility

Inclusion

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com

  • Male and Females 18 years of age or older
  • Pulmonary SCLC documented by histology or cytology
  • Extensive disease (Stage IV) SCLC
  • Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1

Exclusion

  • Prior systemic therapy for lung cancer
  • Symptomatic brain metastases
  • Grade 2 peripheral neuropathy
  • Active or chronic infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV
  • Other active malignancies or prior malignancy within 2 years

Other protocol defined inclusion/exclusion criteria could apply

Inclusion

  • Your cancer has spread to other parts of the body.

Exclusion

  • You have been diagnosed with a prior or secondary type of cancer.
  • You have certain types of non-cancer medical conditions.
  • You have had certain treatments, surgical procedures or drugs.
Message

Clinical trials have complex eligibility criteria.

Ask your doctor if this trial could be right for you.

Participating hospitals

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Completed hospitals

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The Victorian Cancer Trials Link is supported by the Victorian Government through the Victorian Cancer Agency.

RAP

Cancer Council Victoria would like to acknowledge the traditional custodians of the land on which we live and work. We would also like to pay respect to the elders past and present and extend that respect to all other Aboriginal people.