SCOUT : A Phase 1/2 Study of the Oral TRK Inhibitor LOXO-101 (Larotrectinib) in Pediatric Patients With Advanced Solid or Primary Central Nervous System Tumors

Male or<br/>FemaleGender Male or
Female

RecruitingStatus Recruiting

Systemic<br/>Therapy TrialTypeSystemic
Therapy Trial

One/TwoPhase One/Two

<21Age Under 21

Brain and Spinal<br/>CancersCancer LocationBrain and Spinal
Cancers

Systemic therapy | Brain and spinal cordCentral Nervous System

Trial Overview Read MoreRead more

This phase I/II trial is using an oral drug (LOXO-101) as a treatment in children and adolescents with central nervous system tumours.
 

This trial is treating patients with central nervous system tumours.

This is a systemic therapy trial.

You may be able to join this trial if:

  • You have had treatment but your cancer has gotten worse or has not responded to the treatment you have been given.

You may be excluded from this trial if:

  • You have a certain disease or psychological condition.
  • You have had certain treatments, surgical procedures or drugs.
  • You have previously been treated (or are currently being treated) on a clinical trial.

Clinical trials have complex eligibility criteria - talk to your doctor about your interest in this trial.

Clinical Summary Read MoreRead more

Trial Identifiers

Use the hyperlinks, where available to access additional clinical trial information.

Scientific Title

A Phase 1/2 Study of the Oral TRK Inhibitor LOXO-101 (Larotrectinib) in Pediatric Patients With Advanced Solid or Primary Central Nervous System Tumors

Commercial Sponsor

LOXO Oncology, Inc

Summary

This trial has a single group assignment; all participants will receive oral LOXO-101 (larotrectinib) twice daily, with dose adjusted for body surface area (BSA).

Recruiting Hospitals Read MoreRead more

Royal Childrens Hospital
Parkville
Ms Allison Lamb
allison.lamb@rch.org.au
(03) 9345 4989

Trial Overview: General information about a clinical trial. This section provides an overview of who might be able to join this trial and what type of treatment is involved.

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