Trial Identifiers
Use the hyperlinks, where available to access additional clinical trial information.
- ISRCTN71502099, EORTC 1308 / TROG 15.02
Scientific Title
Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial
Other Non-Commercial Sponsor
The Walton Centre NHS Foundation Trust (UK)
Summary
The trial will randomise patients who have undergone gross total surgical resection of atypical (grade II) meningioma in a 1:1 ratio to either early radiotherapy (intervention) or active monitoring (comparator). Web-based randomisation will be used in this trial. Patients will be followed up for 60 months post randomisation by collecting information on signs/symptoms of tumour recurrence, 6 monthly MRI, recording of adverse events, quality of life questionnaires and cognitive function tests.